The epidemiology of prolactinomas. Creating and improving the creative processes. Positive regulation of insulin-like growth factor receptor signaling pathway. One of important task of estrogen is regulating serotonin, dopamine, and norepinephrine pathways However, the evaluated algorithm considered only six out of ten genes. Expert Rev. Hamdieh M 3. These central elements are listed in table 3 and among them, only POMC is from differentially expressed genes.
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Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses. Here, the interaction concept is based on the gene expression profile of a previous study conducted by Tong et al.
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Established best practices of various design problem-solving methodologies, including workshops as part of the design process, followed by user-centered design that included iterative prototyping and experimentation. The significant roles of such highlighted genes on the integrity of the network are corresponding to their possible high impact on the pathology of the disease.
The APN and AD, measures show homogenous decreased trend as the number of clusters increases for hierarchical clustering in which with six clusters has the best overall scores. In this respect, conducting experimental assessments as the validation test is appreciated to examine their potential application in clinical fields.
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|Discussion Prolactinoma, while not malignant, can exert vast adverse effects on the human body Bottlenecks can connect many protein complexes and processes Employed user-centered design methods to understand the existing problems for first time users and delivered delightful design solutions.
Nodes with the highest amount of the designated centrality parameters degree and betweenness of centrality are known as hub-bottlenecks. Naghavi Gargari B 5.
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At last, ten genes see Table 1 concluded for this study, as they were significant in schizophrenia as well.
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Genes with a differential pattern between healthy and Prolactinoma cases were further evaluated, and those with a gene name were used as seed genes for interaction network analysis.
Kappa score was set to 0. PLoS Med. Mahboubi M 1. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4. The height indicates the distance between the nodes.
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|In FOM, the value decreases from two to three clusters but increases afterwards to five clusters and subsequently decreased again to six clusters.
This article has been cited by other articles in PMC. As shown in tables 4 and 5, metabolic and growth regulation are the most highlighted processes of the hub-bottleneck and differentially expressed genes and possibly the outermost disrupted ones.
Earlier investigations highlighted the role of common pathways of The study was conducted by additional analysis of the available data from the GEO database. Protein-protein interaction network analysis for a biomarker panel related to human esophageal adenocarcinoma.